The principal cytochrome P450 isoenzyme associated appears to get CYP2E1, with CYP1A2 and CYP3A4 as further pathways. Close to 85% of an oral dose seems within the urine inside of 24 hours of administration, most as the glucuronide conjugate, with smaller quantities of other conjugates and unchanged drug [see OVERDOSAGE] for toxicity data.Continual